neurodevelopmental disorders + sleep + circadian rhythms
Children with neurodevelopmental disorders frequently have disrupted sleep and circadian rhythms.
In the Cuddapah Lab we seek to understand how this occurs and, in turn, worsens neurological symptoms.
Why does sleep loss exacerbate neurological symptoms?
We are interested in learning why sleep loss increases seizure risk. We seek to understand what ties the sleep state to lethal seizures.
Why do neurological symptoms occur at certain times?
Many neurological symptoms like seizures tend to cluster at particular times of the day. We seek to identify the mechanisms increasing risk of neurological symptoms at certain times.
Is there a genetic basis to sleep/circadian dysfunction?
Our team seeks to understand if there is a genetic basis for sleep or circadian difficulties in people.